2024 The organic anion transporter oat family

The organic anion transporter oat family

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August undefined, 2024

Webbscientific article Webb1 jan. 2015 · The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention …

The multispecific organic anion transporter (OAT) family

WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention … WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention because of … otterbox flip case

Regulation of organic anion transporters: Role in physiology ...

Webb9 juni 2010 · The mycotoxin, ochratoxin A (OTA), is thought to be responsible for Balkan endemic nephropathy. OTA accumulates in several tissues, especially in the kidneys and … The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. It is a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells o… WebbOrganic anion transporters play important roles in the elimination of a variety of endogenous substances, xenobiotics and their metabolites from the body. During the … otterbox flip 4 case

Organic anion transporters and PI3K–AKT–mTOR pathway …

Organic anion transport Pathway - PubChem

WebbFör 1 dag sedan · Organic anion transporters 1 and 3 (OAT1/3) occupy a key role in mediating renal elimination. Kynurenic acid (KYNA) was previously discovered as an … Members of the Organo Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the transport of mainly organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers. OATPs belong to the Solute Carrier Family (SLC) and the major facilitator superfamily. otterbox figura iphone 12WebbMany UTs and drugs administered to CKD patients are organic anions, which are physiologically eliminated by the organic anion transporter (OAT) system [6,7]. OATs … otterbox flip 4

"Webb1 jan. 2006 · Organic anion transporter (OAT) family Gene name Protein name Tissue distribution Predominant substrates SLC22A6 OAT1 kidney PAH, PGE2, urate, NSAIDs, … " - The organic anion transporter oat family

The organic anion transporter oat family

Functional identification of organic cation transporter 1 as an ...

Webb23 juni 2000 · The OAT family represents mainly the renal secretory and reabsorptive pathway for organic anions and is also involved in the distribution of organic anion in the … WebbGene Family The human SCL22 family of transporters encompasses at least 22 members with an additional six structurally related but not yet assigned genes. ... In Vitro and In …

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WebbThe members of the organic anion transporter (OAT) family are mainly expressed in kidney, liver, placenta, intestine, and brain. These transporters play important roles in the … WebbThus, OATs are members of a much larger group of transporters—the SLC22 (solute carrier 22) family—that includes organic cation, carnitine and urate transporters. …

WebbOrganic anion transporters (OATs) and organic cation transporters (OCTs) are members of the superfamily of transporters, Slc (solute carriers). Most are in the families Slc21 … WebbBxPC-3 and MIA PaCa-2 pancreatic cancer cell lines were used to quantify transcripts of OATP 1B1 and 1B3. Results: OATP 1A2, 1B1, and 1B3 proteins were found ubiquitously …

WebbWe explored an atenolol transporter from among the cation or anion transporters. • OCT1 expressed on apical side in enterocytes has transport activity of atenolol. • Transport of … WebbSeveral families of multispecific organic anion and cation transporters, including OAT family transporters, have recently been identified by molecular cloning. The OAT family …

Webb31 dec. 2014 · Open Access The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received …

WebbOATs are multispecific organic anion transporters, the substrates of which include both endogenous (e.g. cyclic nucleotides, prostaglandins, urate, dicarboxylates) and … rockwell collins carlsbadWebb39 rader · 1 jan. 2015 · The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 ... otterbox fold 4 caseWebbOrganic anion transporters (OATs) are shown in red, the organic cation/carnitine transporter (OCTN/CT) family is shown in blue, and organic cation transporters (OCTs) … otterbox folding stand for magsafe chargerWebb1 juni 2000 · Organic anion transporter (OAT) is an heterogenous family of negatively charged proteins, mainly located in kidneys and the liver, but OAT1/OAT3 are also found … otterbox fold 3 caseWebbic anion transporter families, e.g. the organic anion trans-porting polypeptide (oatp) family or the Mrp (multidrug resistance-associated protein) family. On the other hand, the … rockwell collins carlsbad californiaWebb11 apr. 2024 · Glycine synthase (AMT), a solute organic anion transporter family member (OAT), and fatty acyl-coA reductase (FAR) are predicted to be regulated by multiple … rockwell collins charitable givingWebbOATs are multispecific organic anion transporters, the substrates of which include both endogenous (e.g. cyclic nucleotides, prostaglandins, urate, dicarboxylates) and … rockwell collins cedar rapids ia jobs