WebPhenylephrine restored mean arterial pressure but did not increase maternal CO. Oxytocin caused transient marked hypotension, tachycardia, and increases in CO. Topics: cesarean section, hemodynamics, severe pre-eclampsia, spinal anesthesia, oxytocin, phenylephrine, doppler hemodynamics, vasoconstrictor agents, baseline value, mothers WebJul 11, 2024 · Phenylephrine is a direct-acting sympathomimetic amine that functions as an alpha-1 adrenergic agonist. Its chemical structure is related to epinephrine and ephedrine …
PHENYLEPHRINE HCL (Generic for NASAL DECONGESTANT PE)
WebMay 5, 2024 · - Ephedrine may better preserve cerebral blood flow and cerebral oxygenation compared with phenylephrine [ 54-57 ]. • Disadvantages - Tachyphylaxis may occur in patients with depleted stores of endogenous norepinephrine (eg, those with hemorrhagic shock) and may occur with repeated doses. WebSep 24, 2024 · Conversely, ephedrine raises stroke volume and heart rate more than phenylephrine but impairs fetal acid-base status stimulating fetal beta-adrenergic receptors with consequent fetal tachycardia and increased metabolic demand [ 21 ]. Table 17.2 Comparative analysis of vasopressors used in obstetric anesthesia st bernadette\u0027s church new haven ct
Vasopressors in obstetric anesthesia: A current perspective
WebOVERVIEW Vasoactive agents include the following: inotropes are agents that increase myocardial contractility (inotropy) — e.g. adrenaline, dobutamine, isoprenaline, ephedrine vasopressors are agents that cause vasoconstriction leading to increased systemic and/or pulmonary vascular resistance (SVR, PVR) WebMay 5, 2024 · In treating hypotension, cardiovascular effects via the indirect mechanism depend on adequate native norepinephrine stores. Tachyphylaxis will develop with prolonged and repeated use as this depletes endogenous norepinephrine stores. WebMar 1, 2024 · Data indicate that repeated administration of ephedrine can result in tachyphylaxis. Be aware of this possibility when treating anesthesia-induced hypotension with Emerphed and be prepared with an alternative pressor to mitigate unacceptable responsiveness. Risk of Hypertension When Used Prophylactically st bernadette\u0027s church whitefield