Hearts cnp
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ΛΛΛ β§βΛ ε½‘ Web1 de mar. de 2002 Β· CNP markedly enhanced cardiac cGMP content of isolated mouse working hearts, while ANP only had a marginal effect, suggesting that GC-B, a specific CNP receptor, is involved in the responses to CNP. Moreover, cANP (4β23) , a selective ligand of the NPR-C receptor [19] , did not affect cardiac contractility, ruling out CNP effects β¦
Hearts cnp
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Web5 de oct. de 2024 Β· We have previously shown that the natriuretic peptide receptor B (NPR-B) agonist C-type natriuretic peptide (CNP) enhances cyclic adenosine 3Β΄,5Β΄-monophosphate (cAMP)-mediated signaling in failing hearts, through cyclic guanosine 3Β΄,5Β΄-monophosphate (cGMP)-mediated phosphodiesterase (PDE) 3 inhibition.
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